OPTIMIZATION OF NEUROTRANSMITTERS SEPARATION UNDER HILIC CONDITIONS

Authors

  • RALUCA TAMPU “Vasile Alecsandri” University of Bacau, Calea Marasesti 157, Bacau, 600115, Romania
  • CATALIN TAMPU “Vasile Alecsandri” University of Bacau, Calea Marasesti 157, Bacau, 600115, Romania

DOI:

https://doi.org/10.29081/jesr.v23i1.90

Keywords:

catecholamines, HILIC, neurotransmitters

Abstract

This paper presents the optimization of a hydrophilic interaction chromatographic method for the separation of eleven catecholamines, indolamines and their precursors and metabolites. The studied parameters are: the organic modifier nature and percentage, the salt nature and concentration, the mobile phase pH and the column temperature. The best results in terms of separation were obtained using a mobile phase composed of acetonitrile and ammonium formate (150 mM pH 3) 85:15 v:v.

Downloads

Download data is not yet available.

Downloads

Published

2017-03-17

Issue

Vol. 23 No. 1 (2017)

Section

Articles

How to Cite

OPTIMIZATION OF NEUROTRANSMITTERS SEPARATION UNDER HILIC CONDITIONS. (2017). Journal of Engineering Studies and Research, 23(1), 36-41. https://doi.org/10.29081/jesr.v23i1.90

Most read articles by the same author(s)